The Effect of Phyllantus emblica Linn on Type - II Diabetes, Triglycerides and Liver - Specific Enzyme
DOI:
https://doi.org/10.3923/pjn.2009.125.128Keywords:
Alanine transaminase, aqueous fruit extract of P. emblica, cholesterol, triglycerides, type-II diabetesAbstract
The effect of aqueous fruit extract of Phyllanthus emblica Linn was studied on type-II diabetes, triglycerides (TG) and liver-specific enzyme, alanine transaminase (ALT). Our study showed that aqueous fruit extract, in a dose of 200mg/kg body weight, significantly decreased the blood glucose level after its intra-peritoneal administration in alloxan-induced diabetic rats (p<0.05). Almost similar decreased in glucose level was also observed by chlorpropamide, a known antidiabetic drug in a dose of 84 mg/kg. The aqueous extract also induced hypotriglyceridemia by decreasing TG levels at 0, 1, 2 and 4 hours in diabetic rats (p<0.05). In addition, the extract was also found to improve liver function by normalizing the activity of liver-specific enzyme alanine transaminase (ALT).
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