Research Article Open Access

Effect of Trans Fatty Acid on Glucose Level and Pancreatic β Cell in Rats

Authors

CORRESPONDING AUTHOR
R.A.D. Sartika
Department of Public Health Nutrition, Faculty of Public Health, University Indonesia, Depok, West Java, 16424, Indonesia
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K. Achmad
Department of Public Health Nutrition, Faculty of Public Health, University Indonesia, Depok, West Java, 16424, Indonesia
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Triyanti
Department of Public Health Nutrition, Faculty of Public Health, University Indonesia, Depok, West Java, 16424, Indonesia
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Rustika
National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia
Published on: July 15, 2016
DOI 10.3923/pjn.2016.760.762
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Abstract

A high intake of trans fatty acids can cause inflammation and lipid peroxidation of cell membranes which, in turn, damage cells and tissues. The purpose of the current study was to investigate the effects of dietary trans fatty acids on blood glucose levels and pancreatic β cells. Our randomized pre-post test control group study design included two groups of Wistar rats fed either a diet containing 2% trans fat or a control diet containing no trans fat for 10 d. The results showed that blood glucose levels were not significantly different between the two groups. There was no obvious damage to pancreatic β cells, but the number of normal cells in the treatment group was less than that in control animals.

Keywords:

Blood glucose, pancreatic β cell, trans fatty acid

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Copyright (c) 2016 Asian Network for Scientific Information

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This work is licensed under a Creative Commons Attribution 4.0 International License.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

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How to Cite

Sartika, R., Achmad, K., Triyanti, & Rustika. (2016). Effect of Trans Fatty Acid on Glucose Level and Pancreatic β Cell in Rats. Pakistan Journal of Nutrition, 15(8), 760–762. https://doi.org/10.3923/pjn.2016.760.762
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