Research Article Open Access

Effect of International and Indonesian Fast Foods on Plasma Ghrelin and Glucagon Like Peptide-1 (GLP-1) Levels, Hunger and Satiety Scores is Similar in Obese Adults

Authors

CORRESPONDING AUTHOR
D. Handayani
Nutrition Study Program, Faculty of Medicine, University of Brawijaya, Malang, Indonesia
|
L.D.A. Oktafiani
Biomedical Postgraduate Study Program, Faculty of Medicine, University of Brawijaya, Malang, Indonesia
|
R.T. Abednego
Biomedical Postgraduate Study Program, Faculty of Medicine, University of Brawijaya, Malang, Indonesia
|
S. Andarini
Laboratory of Public Health, Faculty of Medicine, University of Brawijaya, Malang, Indonesia
Published on: December 15, 2016
DOI 10.3923/pjn.2017.38.44
PDF

Abstract

Background and Objective: The desire for food is regulated by appetite-associated hormones such as ghrelin and glucagon-like peptide-1 (GLP-1). Hormone release is influenced by the energy density of and macro-nutrients in food. This study assessed the effects of international and Indonesian fast food on ghrelin and GLP-1 levels, which contribute to the perception of hunger and satiety, in obese individuals. Materials and Methods: A total of 16 obese individuals were provided international fast food; after a week, the subjects were provided Indonesian fast food. Plasma samples were collected and the perceptions of hunger and satiety were assessed using a visual analogue scale before consuming time 0, 30, 60 and 120 min after consuming both kinds of fast food. Data were analyzed using unpaired t-tests, Mann-Whitney U tests, Pearson’s correlation coefficients and Spearman’s rank correlation coefficients. Results: The results revealed significant decreases in plasma ghrelin levels after 120 min of eating international and Indonesian fast foods. In contrast, plasma glucagon-like peptide-1 hormone levels did not differ significantly after consuming both kinds of fast food. The results also showed no correlation between changes in the plasma levels of ghrelin and GLP-1 and the perceptions of hunger and satiety in obese individuals. Conclusion: It is concluded that both types of fast food resulted in equal suppression of hunger and increased satiety.

Keywords:

Ghrelin, GLP-1, Indonesian fast food, international fast food, obesity, VAS

Article Metrics

219 Abstract Views
139 File Views
0 Downloads

License

Copyright (c) 2017 The Author(s)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

Article Citation Metrics

Find Effect of International and Indonesian Fast Foods on Plasma Ghrelin and Glucagon Like Peptide-1 (GLP-1) Levels, Hunger and Satiety Scores is Similar in Obese Adults on PlumX

How to Cite

Handayani, D., Oktafiani, L., Abednego, R., & Andarini, S. (2016). Effect of International and Indonesian Fast Foods on Plasma Ghrelin and Glucagon Like Peptide-1 (GLP-1) Levels, Hunger and Satiety Scores is Similar in Obese Adults. Pakistan Journal of Nutrition, 16(1), 38–44. https://doi.org/10.3923/pjn.2017.38.44
Crossref
Scopus
Google Scholar
Europe PMC

References

1.
Kemenkes BPdPK, 2013. Riset kesehatan dasar. BPdPK, Kemenkes, Jakarta. http://dinkes.bantenprov.go.id/upload/article_doc/Hasil_Riskesdas_2013.pdf.
2.
Salmenkallio-Marttila, M., A. Due, I. Gunnarsdottir, L. Karhunen, M. Saarela and M. Lyly, 2008. Satiety, weight management and foods: Literature review. Nordic Innovation Centre, Oslo, Norway, January 2008, pp: 1-160.
3.
World Health Organization, 2004. Obesity: Preventing and managing the global epidemic. Technical Report Series 894, WHO Consultation, USA., pp: 1-253.
4.
Indra, M.R., 2006. Dasar genetik obesitas viseral. J. Kedokteran Brawijaya, 22: 10-17.
5.
Guthrie, J., B.H. Lin and E. Frazao, 2002. Role of food prepared away from home in the American diet, 1977-78 versus 1994-96: Changes and consequences. J. Nutr. Educ. Behav., 34: 140-150.
6.
Ashakiran and R. Deepthi, 2012. Fast foods and their impact on health. JKIMSU., 1: 7-15.
7.
Worthington-Roberts, B.S. and S.R. Williams, 2000. Nutrition Throughout the Life Cycle. 4th Edn., McGraw-Hill, New York, USA., ISBN: 9780072927320, Pages: 469.
8.
Sharkey, J., C.M. Johnson, W.R. Dean and S.A. Horel, 2011. Association between proximity to and coverage of traditional fast-food restaurants and non-traditional fast-food outlets and fast-food consumption among rural adults. Int. J. Health Geogr., Vol. 10.
9.
Handayani, D., B.J. Meyer, J. Chen, S.H.J. Brown, T.W. Mitchell and X.F. Huang, 2014. A high-dose shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: Underlying mechanism. Nutrients, 6: 650-662.
10.
Holst, J.J., 2007. The physiology of glucagon-like peptide 1. Phys. Rev., 87: 1409-1439.
11.
Flint, A., A. Raben, J.E. Blundell and A. Astrup, 2000. Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int. J. Obes. Relat. Metab. Disord., 24: 38-48.
12.
Flint, A., B.K. Moller, A. Raben, B. Sloth, D. Pedersen, I. Tetens, J.J. Holst and A. Astrup, 2006. Glycemic and insulinemic responses as determinants of appetite in humans. Am. J. Clin. Nutr., 84: 1365-1373.
13.
Handayani, D., W. Rahmawati, I. Kusumastuty, L.B. Harti, E.S. Wahyuni and S. Andarini, 2016. Plasma ghrelin, PYY and CCK concentration following Indonesian fast food and Western fast food in obese participant. Food Nutr. Sci., 7: 724-731.
14.
Handayani, D., J. Chen, B.J. Meyer and X.F. Huang, 2011. Dietary shiitake mushroom (Lentinus edodes) prevents fat deposition and lowers triglyceride in rats fed a high-fat diet. J. Obes.
15.
Cummings, D.E., J.Q. Purnell, R.S. Frayo, K. Schmidova, B.E. Wisse and D.S. Weigle, 2001. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes, 50: 1714-1719.
16.
Taylor, K., K. Gurney, J. Han, R. Pencek, B. Walsh and M. Trautmann, 2011. Exenatide once weekly treatment maintained improvements in glycemic control and weight loss over 2 years. BMC Endocr. Disord., Vol. 11.
17.
Hill, B.R., B.J. Rolls, L.S. Roe, M.J. de Souza and N.I. Williams, 2013. Ghrelin and peptide YY increase with weight loss during a 12-month intervention to reduce dietary energy density in obese women. Peptides, 49: 138-144.
18.
Luscombe-Marsh, N.D., R.V. Seimon, E. Bollmeyer, J.M. Wishart and G.A. Wittert et al., 2013. Acute effects of oral preloads with increasing energy density on gastric emptying, gut hormone release, thermogenesis and energy intake, in overweight and obese men. Asia Pac. J. Clin. Nutr., 22: 380-390.
19.
Rolls, E.T., 2010. Taste, Olfactory and Food-Texture Processing in the Brain and the Control of Appetite. In: Obesity Prevention: The Role of Brain and Society on Individual Behavior, Dube, L., A. Bechara, A. Dagher, A. Drewnowski, J. LeBel, P. James and R.Y. Yada (Eds.). Chapter 4, Academic Press, UK., ISBN-13: 9780080922096, pp: 41-56.
20.
Karl, J.P., A.J. Young, J.C. Rood and S.J. Montain, 2013. Independent and combined effects of eating rate and energy density on energy intake, appetite and gut hormones. Obesity, 21: E244-E252.
21.
McNeil, J., V. Drapeau, A.R. Gallant, A. Tremblay, E. Doucet and J.P. Chaput, 2013. Short sleep duration is associated with a lower mean satiety quotient in overweight and obese men. Eur. J. Clin. Nutr., 67: 1328-1330.
22.
Erdmann, J., R. Topsch, F. Lippl, P. Gussmann and V. Schusdziarra, 2004. Postprandial response of plasma ghrelin levels to various test meals in relation to food intake, plasma insulin and glucose. J. Clin, Endrocrinol. Metab., 89: 3048-3054.
23.
Klok, M.D., S. Jakobsdottir and M.L. Drent, 2007. The role of leptin and ghrelin in the regulation of food intake and body weight in humans: A review. Obes. Rev., 8: 21-34.
24.
Chanoine, J.P., K.J. Mackelvie, S.I. Barr, A.C. Wong, G.S. Meneilly and D.H. Elahi, 2008. GLP-1 and appetite responses to a meal in lean and overweight adolescents following exercise. Obesity, 16: 202-204.
25.
Ranganath, L.R., J.M. Beety, L.M. Morgan, J.W. Wright, R. Howland and V. Marks, 1996. Attenuated GLP-1 secretion in obesity: Cause or consequence? Gut, 38: 916-919.
26.
Anini, Y. and P.L. Brubaker, 2003. Role of leptin in the regulation of glucagon-like peptide-1 secretion. Diabetes, 52: 252-259.