Histomorphology of Testes in Honey Treated Adult Male Albino Rats
Authors
- Anulika O. Onyemelukwe Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
- Rita I-O. Ogu Department of Human Physiology, Faculty of Basic Medical Sciences, University of Science and Technology, Enugu State, Nigeria
- Nkiruka C. Azubuike Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
-
Cornelius O. Ogu
Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
- Okechukwu S. Onwukwe Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
- Udoh P. Iniekong Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
- Basil C. Udeh Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
- Peter U. Achukwu Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
- Ikenna K. Uchendu Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, University of Nigeria, Enugu Campus, Enugu, Nigeria
DOI:
https://doi.org/10.3923/pjn.2023.88.94Keywords:
Albino rats, honey, leydig cells, sertoli cells, testes, testicular tissues, testosteroneAbstract
Objective: Present study was conducted to examine the histomorphology of testes and serum testosterone levels of adult male albino rats fed with honey. Materials and Methods: The albino rats were divided into four groups of eight per cage. Controls received drinking water. Groups A, B and C were fed with 0.15, 0.3 and 0.6 mL kg–1 b.wt. of honey respectively twice a day, orally for four and eight weeks. Blood samples were obtained from 4 rats per group for testosterone estimation. Testes were excised for histomorphology. Results: After eight weeks, testes from control and honey-treated rats showed normal histoarchitecture, whereas four-week honey-treated rats showed decreased prominence of seminiferous tubules with prominent sertoli cells and reduction of leydig cells. After four weeks, honey-treated rats showed significant elevation in serum testosterone level (p<0.05), but after eight-week, no significant change (p>0.05) was observed, compared to controls. Conclusion: Honey consumption could have a short-term positive effect on testosterone secretion and may lead to hyperactive testicular cells.
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