HOMA-IR Anomalies and Sugar Consumption in Young with Euglycemia

Abstract

The aim of this study was to assess sugar consumption through a 24 h recall questionnaire, its quantification was performed with a Web-based application and then correlated with HOMA-IR. Seventy-four women and fifty-two men participated in the study, x̄ 18 years old. Data were retrieved from the 24 h recall questionnaire and the amount of sugar in food and drinks was quantified. The quantities of sugar were assessed with the online application of www.fatsecret.com.mx. Likewise, we quantified glucose, triglycerides, total cholesterol, insulin, C peptide and glycosylated hemoglobin. Fifty-two (41.3%) participants presented biomarkers within desirable levels and 74 (58.7%) presented at least one value within the risk level. There were no significant differences in the average values of body mass index, waist-hip and waist-size indices between those with desirable values and those with anomalies. Among the young population with biomarkers within desirable values, 10% presented abnormal insulin and HOMA-IR values; besides, 25% of them had glycosylated hemoglobin values of >6.2%. There was a correlation between sugar consumption and HOMA-IR, (p = 0.007). In the young population with euglycemia, anomalies in HOMA-IR and glycosylated hemoglobin values can be found. Assessment of elevated dietary sugar consumption could predict anomalies in glycosylated hemoglobin and HOMA-IR.