Research Article Open Access

Effect of Dietary Habits on Serum Zinc Level in Patients with Inflammatory Bowel Disease During Remission Phase

Authors

Ruaa E. Alabd
Al Zeweya Primary Health Care Center, Baghdad, Iraq
|
CORRESPONDING AUTHOR
Hayder G. Oufi
iD 0000-0002-7465-6374
College of Pharmacy, Al-Turath University, Baghdad, Iraq
|
Nawal Mehdi Firhan Alkhalidi
GIT Teaching Hospital Medical City, Baghdad, Iraq
Published on: December 30, 2024
DOI 10.3923/pjn.2024.73.80
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Abstract

Background and Objective: In ulcerative colitis and Crohn’s disease, low zinc levels can worsen gastrointestinal symptoms. However, there is ongoing debate regarding zinc levels in individuals with Inflammatory Bowel Disease (IBD). The aim of this study was to investigate the relationship between dietary habits and serum zinc levels in patients with Inflammatory Bowel Disease (IBD) during remission and to identify potential factors contributing to zinc deficiency in this population. Materials and Methods: A retrospective cohort study was conducted at two hospitals, including 60 patients with IBD and 30 healthy controls. All participants completed a dietary questionnaire and serum zinc levels were measured. Results: Patients with Crohn’s disease and ulcerative colitis had significantly lower serum zinc levels compared to the control group. Regression analysis identified two significant determinants of lower zinc levels: being female and having any form of IBD. Conclusion: The study found that female sex and the presence of any form of IBD were associated with lower serum zinc levels. Dietary intake did not significantly influence zinc levels. It may be crucial to monitor zinc levels in IBD patients, particularly women, for proper management.

Keywords:

Crohn’s disease, diet, dietary pattern, ulcerative colitis, zinc

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Alabd, R. E., Oufi, H. G., & Firhan Alkhalidi, N. M. (2024). Effect of Dietary Habits on Serum Zinc Level in Patients with Inflammatory Bowel Disease During Remission Phase. Pakistan Journal of Nutrition, 23, 73–80. https://doi.org/10.3923/pjn.2024.73.80
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