The Effect of α-tocopherol on Cholesterol and Lipoproteins Levels in Rats

Abstract

The effect of the α-tocopherol on the reduction of plasma cholesterol, HDL, and LDL have been investigated in rats. No significant differences were observed on the rate of body weight gain, food intake, and food efficiency of rats fed with diet supplemented with α-tocopherol. There were significant decreases in serum cholesterol, and LDL+VLDL of animals fed α-tocopherol supplementation compared to control. In contrast the HDL cholesterol showed no significant decrease in animal groups fed α-tocopherol compared to control group. The lowest bile acid levels were in feces of control group, and the highest levels were for the groups fed α-tocopherol supplementation.