Dietary Calcium Had No Reducing Effect on Body Fat and Weight Gain in Sprague-Dawley Rats

Authors

  • J.M. Malekzadeh Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • S.A. Keshavarz Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • F. Siassi Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • M. Eshraghian Department of Epidemiology and Statistics, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • M. Kadkhodaee Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  • A.R. Dorosty Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  • A. Aliehpour Shariaati Hospital of Tehran, Tehran University of Medical Sciences, Tehran, Iran
  • M. Chamari Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran, Iran

DOI:

https://doi.org/10.3923/pjn.2007.478.484

Keywords:

Body fat, dietary calcium, PTH, weight

Abstract

Recently, studies have focused on the effects of dietary calcium on the weight and fatness. Some of these studies have indicated that there is negative relationship between dietary calcium and body fat, while others have reported no such effects. There are also controversies over serum parathyroid hormone, as its mechanism, on body fat and weight. The objective of the present study was to evaluate the effects of three dietary calcium levels (0.2%, 0.5% or 1.2% Ca2+) on body fat and weight gain in male Sprague-Dawley rats, using same diet composition for nutrients other than calcium. The study duration was 72 days. At the end, truncal blood samples were drawn from decapitated rats to measure the effects of diets on serum calcium, PTH and vitamin D. The carcasses were minced and homogenized to measure their body fat percent by the methods of Soxhelet. There were no significant effects of dietary calcium on food intake (p>0.05), body weight gain (p>0.05) or carcass fat content (p>0.05), while the serum PTH levels were inversely related to calcium intake (p<0.05). In conclusion, our findings do not support the effects of dietary calcium and parathyroid hormone on body fat and weight.

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Published

15.08.2007

Issue

Vol. 6 No. 5 (2007)

Section

Research Article

License

Copyright (c) 2007 Asian Network for Scientific Information

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

How to Cite

Malekzadeh, J., Keshavarz, S., Siassi, F., Eshraghian, M., Kadkhodaee, M., Dorosty, A., Aliehpour, A., & Chamari, M. (2007). Dietary Calcium Had No Reducing Effect on Body Fat and Weight Gain in Sprague-Dawley Rats. Pakistan Journal of Nutrition, 6(5), 478–484. https://doi.org/10.3923/pjn.2007.478.484