Effect of Acalypha wilkesiana Muell Arg on Plasma Sodium and Potassium Concentration of Normal Rabbits
Abstract
The effect of Acalypha wilkesiana leaves on plasma levels of sodium and potassium were studied in normal rabbits given daily, by intra-gastric gavage, 1g/kg of the leaf, in the form of decoction prepared by mixing 5g of air-dried powdered leaves in 10 mL water. The treatment led to significant decreases (p<0.05) in plasma sodium concentrations and significant increases in potassium concentrations. These findings connote a therapeutic advantage in the use of A. wilkesiana for the treatment of hypertension, especially in managing the abnormal sodium and potassium metabolisms that accompany hypertension.
Keywords:
Acalypha wilkesiana, hypertension, potassium-sparing diureticArticle Metrics
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