Toxicity of Anagallis arvensis Plant

Authors

  • S.I. Al-Sultan Department of Public Health and Animal Husbandry, College of Veterinary Medicine and Animal Resources, King Faisal University, P.O. Box 11647, AI-Ahsa 31982, Saudi Arabia
  • Y.A. Hussein Department of Clinical Studies, College of Veterinary Medicine and Animal Resources, King Faisal University, P.O. Box 11647, AI-Ahsa 31982, Saudi Arabia
  • A. Hegazy Department of Pathology, College of Veterinary Medicine and Animal Resources, King Faisal University, P.O. Box 11647, AI-Ahsa 31982, Saudi Arabia

DOI:

https://doi.org/10.3923/pjn.2003.116.122

Keywords:

Anagallis arvensis, Rat, Alcohlic extracts, Saudi Arabia

Abstract

Sixty adult rats of both sexes were used for determination of LD50 of Anagallis arvensis. Other eighteen rats were used for repeated successive dose for determination of blood picture, kidney function and histopathological changes associated with A. arvensis toxicosis (1/5 and 1/10 LD50) IP for 15 days. The LD50 was 10.718 mg/kg.b.wt. of alcoholic extract of A. arvensis. The clinical signs included anorexia, restlessness, diarrhea, thirst, difficult breathing, tremors and ended by coma and death. Hematologically, there were a significant reduction in PCV%, Hb concentration and RBCs count of the intoxiced rats. Concerning kidney function tests, there were a significant increase in urea and creatinine level of the intoxicated rats. Pathologically, the lesions were primarily confined to the urinary system.

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Published

15.04.2003

Issue

Vol. 2 No. 3 (2003)

Section

Research Article

License

Copyright (c) 2003 Asian Network for Scientific Information

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.

How to Cite

Al-Sultan, S., Hussein, Y., & Hegazy, A. (2003). Toxicity of Anagallis arvensis Plant. Pakistan Journal of Nutrition, 2(3), 116-122. https://doi.org/10.3923/pjn.2003.116.122