Effect of Small Peptide Chelate Chromium on Growth Performance, Organ Development and Serum Traits in Spargue-Dawley Rats

Abstract

The experiment was conducted to study the effect of supplementing Small Peptide Chelate Chromium (SPCr) in diets on growth performance, organ development and serum traits in Spargue-Dawley rats. Seventy two SD rats with initial body weight about (65±5 g) were randomly assigned to six dietary treatment, basal diet, basal diet supplemented with 100, 200, 500 or 1000 μg/kg Cr in the form of SPCr and 200 μg/kg Cr in the form of chromium picolinate (CrPic). Each treatment had 6 replicates. The duration of the study was 35 days. The results showed that: Supplementation of Cr with different types at low-level (below 500 μg/kg) increased daily gain and feed efficiency. Supplementation of 500 μg/kg SPCr increased ADG (p<0.05), decreased feed:gain ratio (p<0.05) compared with control group. Serum cholesterol and triglyceride was decreased(p<0.05) fed diets with SPCr at low-level. Supplementation of Cr with different types increased serum high density lipoprotein (p<0.05), also decreased serum glucose and insulin compared with control group. Addiction of Cr with different types increased the relative weights of liver (p<0.05). It was concluded that SPCr had effect to improve performance and serum lipids.