Clinical Study for UNECE U-168, an Enteral Nutritional Formula for Patients Receiving Long-Term Nasogastric Tube Feeding

Authors

  • Pei-Yu Wu School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan
  • Chuan-Ching Lan New Bellus Enterprises Co., Ltd., Tainan, Taiwan
  • Shwu-Huey Yang School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan

DOI:

https://doi.org/10.3923/pjn.2015.758.761

Keywords:

Enteral nutritional formula, malnutrition, nasogastric tube feeding, UNECE U-168

Abstract

The objective of this study was to examine the effect of UNECE U-168, an enteral nutrient formula on the nutritional status and renal or hepatic function. During November, 2009 to May, 2011, 30 participants (13 males and 17 females; average age 73.7±15.1 years) were recruited from five nursing homes in New Taipei City, Taiwan. All participants had been on nasogastric tube feeding for three months or more. For four weeks, UNECE U-168 (1500 Kcal) enteral nutritional formula was given to participants as part of their diet. Anthropometric and biochemical measurements were performed. Differences of the measurements before and the nutritional intervention were compared. After 4 weeks of UNECE U-168 enteral nutritional formula as diet, body weight and BMI were stable. Nutritional indicators including serum albumin and total protein levels were maintained at similar levels. Total triglyceride and low-density lipoprotein cholesterol levels had a significant decrease (p<0.05). Aspartate transferase, alanine transaminase and alkaline phosphatase showed normal values. In addition, creatinine and blood urea nitrogen levels were all within the normal range. UNECE U-168 enteral nutritional formula can maintain the nutritional status in diabetic patients and have no adverse effects on the hepatic and renal function.

References

Chang, C.C. and B.L. Roberts, 2011. Malnutrition and feeding difficulty in Taiwanese older with dementia. J. Clin. Nur., 20: 2153-2161.

Chang, H., L. Shi, Y. Hsieh and Y. Tsaur, 1999. The applicability of knee length for height estimation for clinical evaluation. Proceedings of the 25th Annual Conference of the Taiwan Society Nutrition Studies, March 26-30, 1999, Taipei, Taiwan.

Davalos, A., W. Ricart, F. Gonzalez-Huix, S. Soler and J. Marrugat et al., 1996. Effect of malnutrition after acute stroke on clinical outcome. Stroke, 27: 1028-1032.

Davies, A.R., P.R. Froomes, C.J. French, R. Bellomo and G.A. Gutteridge et al., 2002. Randomized comparison of nasojejunal and nasogastric feeding in critically ill patients. Critical Care Med., 30: 586-590.

DiMaria-Ghalili, R.A. and E. Amella, 2005. Nutrition in older adults: Intervention and assessment can help curb the growing threat of malnutrition. Am. J. Nurs., 105: 40-50.

Eckerwall, G., J.B. Axelsson and R.G. Andersson, 2006. Early nasogastric feeding in predicted severe acute pancreatitis: A clinical, randomized study. Ann. Surg., 244: 959-967.

Erdman, Jr.J.W., 2000. AHA science advisory: Soy protein and cardiovascular disease. A statement for healthcare professionals from the nutrition committee of the AHA. Circulation, 102: 2555-2559.

Kane, R.A., 2003. Definition, measurement and correlates of quality of life in nursing homes: Toward a reasonable practice, research and policy agenda. Gerontologist, 43: 28-36.

Norton, B., M. Homer-Ward, M.T. Donnelly, R.G. Long and G.K.T. Holmes, 1996. A randomised prospective comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding after acute dysphagic stroke. Br. Med. J., 312: 13-16.

Okada, K., H. Yamagami, S. Sawada, M. Nakanishi and M. Tamaki et al., 2001. The nutritional status of elderly bed-ridden patients receiving tube feeding. J. Nutr. Sci. Vitaminol., 47: 236-241.

Park, R.H., M.C. Allison, J. Lang, E. Spence and A.J. Morris et al., 1992. Randomised comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding in patients with persisting neurological dysphagia. Br. Med. J., 304: 1406-1409.

Reynolds, K., A. Chin, K.A. Lees, A. Nguyen, D. Bujnowski and J. He, 2006. A meta-analysis of the effect of soy protein supplementation on serum lipids. Am. J. Cardiol., 98: 633-640.

Stange, I., K. Poeschl, P. Stehle, C.C. Sieber and D. Volkert, 2013. Screening for malnutrition in nursing home residents: Comparison of different risk markers and their association to functional impairment. J. Nutr. Health Aging, 17: 357-363.

Yang, W.C. and S.J. Hwang, 2008. Incidence, prevalence and mortality trends of dialysis end-stage renal disease in Taiwan from 1990 to 2001: The impact of national health insurance. Nephrology Dialysis Transplantation, 23: 3977-3982.

Yeh, C.J., H.Y. Chang and W.H. Pan, 2011. Time trend of obesity, the metabolic syndrome and related dietary pattern in Taiwan: From NAHSIT 1993-1996 to NAHSIT 2005-2008. Asia Pacific J. Clin. Nutr., 20: 292-300.

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Published

15.10.2015

Issue

Section

Research Article

How to Cite

Wu, P.-Y., Lan, C.-C., & Yang, S.-H. (2015). Clinical Study for UNECE U-168, an Enteral Nutritional Formula for Patients Receiving Long-Term Nasogastric Tube Feeding. Pakistan Journal of Nutrition, 14(11), 758–761. https://doi.org/10.3923/pjn.2015.758.761

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