Research Article Open Access

Evaluation of in-vitro Antioxidant Activities of Methanol Extracts of Persea americana and Cnidosculus aconitifolius

Authors

CORRESPONDING AUTHOR
M.F. Asaolu
Department of Biochemistry, University of Ado-Ekiti, P.M.B. 5363, Ado- Ekiti, Nigeria
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S.S. Asaolu
Department of Chemistry, University of Ado-Ekiti, P.M.B. 5363, Ado-Ekiti, Nigeria
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J.B. Fakunle
Department of Chemical Pathology, Obafemi Awolowo University, Ile-Ife, Nigeria
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B.O. Emman-Okon
Department of Chemical Pathology, Obafemi Awolowo University, Ile-Ife, Nigeria
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E.O. Ajayi
Department of Chemical Pathology, Obafemi Awolowo University, Ile-Ife, Nigeria
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R.A. Togun
Department of Heamatology and Immunology, Obafemi Awolowo University, Ile-Ife, Nigeria
DOI 10.3923/pjn.2010.1074.1077
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Abstract

The present study was undertaken to investigate the antioxidant activities of Persea americana and Cnidosculous aconitifolius. The in-vitro antioxidant activity of the methanol extracts of the leaves of Persea americana and Cnidosculous aconitifolius was evaluated using various experimental methods such as 1,1-diphenyl-2-picryl-hydrazyl (DPPH), nitric oxide and reducing power radical- scavenging activity assay. Phytochemical screening as well as the amounts of total phenol and flavonoids were also determined. The present study revealed that both the methanol extracts of the leaves of Persea americana and Cnidosculous aconitifolius possess significant antioxidant activities. However, Persea americana was found to have higher radical scavenging activity than Cnidosculous aconitifolius but the phenol content of Cnidosculous aconitifolius was higher than that of Persea americana whereas Persea americana was observed to possess more flavonoids than Cnidosculous aconitifolius.

Keywords:

Antioxidant activities, methanol extracts, phytochemical screening, radical-scavenging activity

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Asaolu, M., Asaolu, S., Fakunle, J., Emman-Okon, B., Ajayi, E., & Togun, R. (2010). Evaluation of in-vitro Antioxidant Activities of Methanol Extracts of Persea americana and Cnidosculus aconitifolius. Pakistan Journal of Nutrition, 9(11), 1074–1077. https://doi.org/10.3923/pjn.2010.1074.1077