Effect of Jaman Fruit Extract on Serum Glucose and Lipid Profile in Type 2 Diabetic Individuals

Abstract

The effect of jaman fruit extract on glucose and lipid was studied in 10 type 2 diabetic individuals of both sexes for 12 days. Whole jaman fruit extract was prepared in distilled water. The insoluble residue was separated by filtration. Two gram potassium-metabisulphite and 30 g citric acid/L was added to the extract as preservatives. The extract was stored at room temperature for use. Ninety ml extract was given to the diabetic subjects in 3 doses per day after breakfast, lunch and dinner. Fasting blood samples were collected from the subjects on day 0, during the experiment (days 4 and 8) and 4 days after the stoppage of jaman extract (day 12). Serum glucose, TGL, total, HDL and LDL cholesterol were determined. After consumption of jaman extract, there was decrease in serum glucose in some individuals but not significant. Similar pattern was observed in serum TGL. Total cholesterol was decreased, but non-significantly. Also LDL was non-significantly decreased. HDL was not affected. The serum glucose, total cholesterol and LDL were lower on day 12, when the individuals were not using jaman extract, than the values for these parameters on day 0, when the individuals had not started yet the intake of jaman extract, making a clue that the extract effect may be appearing after some time. The results of this study are not conclusive, may be due to the preservatives used or short experimental period. Studies on jaman extract without preservatives and for longer durations are suggested.