Potential of Pigmented Rice Enriched with Kappa-Carrageenan and Anthocyanin Extract For Glycaemic Property Improvements in Diabetic Rats
DOI:
https://doi.org/10.3923/pjn.2016.374.378Keywords:
Anthocyanin extract, diabetic rats, kappa-carrageenan, pigmented riceAbstract
The objective of this study was to evaluate the glycaemic property of diabetic rats after consumption of enriched pigmented rice. During the experiment, thirty 2.5-month-old male Wistar rats with 175-250 g body weights were divided into 6 groups (n = 6) and fed Mandel Handayani pigmented rice enriched with 2% kappa-carrageenan and anthocyanin extract from black rice (5 ml/100 g pigmented rice) and standard feed AIN 93 for maintenance. After 5 days of adaptation, diabetes was induce using STZ and nicotinamide and treatment was started 5 days afterwards for 6 weeks. The observed parameters were feed remains and efficiency, body weight, blood glucose level, serum insulin assayed using a rat ELISA insulin kit and Homa IR and Homa β analyses. The results showed that both pigmented rice and kappa-carrageenan and anthocyanin-enriched pigmented rice improved the glycaemic properties of diabetic rats, as indicated by increases in rat body weight of between 10.14 and 11.94%, with feed efficiency ranging between 13.62 and 17.39%, reduced and stabilized blood glucose levels, increased insulin levels, reduced insulin resistance (HOMA IR) and improved pancreatic β cell function (HOMA β).
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